Mechanism of action
The exceptional nature of the mechanism of action is based on the synergy of these 3 ingredients which together generate the highly protective and filmogenous action:
Hyaluronic Acid plays a fundamental role in every phase of tissue repair, including inflammation, cell migration, angiogenesis, re-epithelialization and has a film genic ability
Hydrogen Peroxide has the high antibacterial, antiviral and anti-mycotic action
Glycine is able to accelerate the cutaneous barrier repair.
A product based on Hydrogen peroxide and Hyaluronic acid indicated to maintain a moist environment that is conducive to healing, by either absorbing wound exudate or donating moisture. Thanks to its antimicrobial agents, it inhibits the growth of micro-organisms.
Key ingredients work synergistically to create the highly protective and filmogenous barrier.
HA is found in many tissues of the body and is a major component of the extracellular matrix. It is involved in numerous physiological processes, such as cell proliferation, cellular function, tissue hydration, and joint lubrication.
HA also plays a fundamental role in every phase of tissue repair, including inflammation, cell migration, angiogenesis, re-epithelialization and scar formation due to its physico-chemical (hygroscopic, rheological and viscoelastic) and biological properties. Hyaluronic acid-based medications have been found to facilitate wound repair and have proved more effective than growth factors in promoting healing while also reducing scar formation.
Subsequently, HA has become widely used not only to improve wound healing, but also as a medical treatment and prevention for a large number of the following connective tissue disorders and problems: fractures, hernias, glaucoma, keratoconus, detached retinas, osteoarthritis, TMJ, vocal cord insufficiency, cartilage damage, and ligament healing. Moreover, it provides soothing relief of dryness, itching, and burning of the skin.
Hydrogen peroxide is a strong oxidizing agent, effective against a wide range of micro-organisms, with high antibacterial, antiviral and anti-mycotic action.
It kills bacteria by damaging their DNA, which is highly susceptible to oxidative damage, with highly reactive hydroxyl radicals. Hydrogen peroxide is also part of the innate immune response to fight infection and foreign invaders of the body.
Neutrophils, the most abundant type of phagocyte in the body, are usually the first cells to arrive at the site of an infection and produce hydrogen peroxide to attack toxins, parasites, bacteria, viruses and yeasts.
Glycine is a non-essential amino acid and has anti-inflammatory, cytoprotective and immunomodulation properties.
It is a fundamental component of several important biological molecules, such as collagen and acts as a biosynthetic intermediate in numerous metabolic reactions.
Current research has demonstrated that endothelial and epithelial cells contain glycine-dependent chlorine channels and that when these channels are stimulated, cutaneous barrier repair is accelerated, indicating that glycine plays a crucial role in skin barrier homeostasis.